HVEM has a broader expression than PD-L1 and constitutes a negative prognostic marker and potential treatment target for melanoma

Nausicaa Malissen,Nicolas Macagno,Samuel Granjeaud,Clémence Granier,Vincent Moutardier,Caroline Gaudy Marqueste,Nadia Habel,Marion Mandavit,Bernard Guillot,Christine Pasero,Eric Tartour,Robert Ballotti,Jean-Jacques Grob,Daniel Olive

HVEM has a broader expression than PD-L1 and constitutes a negative prognostic marker and potential treatment target for melanoma

2019

Nausicaa Malissen
Nicolas Macagno
Samuel Granjeaud
Clémence Granier
Vincent Moutardier
Caroline Gaudy Marqueste
Nadia Habel
Marion Mandavit
Bernard Guillot
Christine Pasero
Eric Tartour
Robert Ballotti
Jean-Jacques Grob
Daniel Olive

ABSTRACTHVEM (Herpes Virus Entry Mediator) engagement of BTLA (B and T Lymphocyte Attenuator) triggers inhibitory signals in T cells and could play a role in evading antitumor immunity. Here, HVEM ...

Keywords:

Cancer research
PD-L1
Medicine
Melanoma
Immunology
t lymphocyte
Mediator
herpes virus
Microphthalmia-associated transcription factor
BTLA
treatment targets

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