AMD Classification in Choroidal OCT Using Hierarchical Texton Mining

In this paper, we propose a multi-step textural feature extraction and classification method, which utilizes the feature learning ability of Convolutional Neural Networks (CNN) to extract a set of low level primitive filter kernels, extracts spatial information using clustering and Local Binary Patterns (LBP) and then generalizes the discriminative power by forming a histogram based descriptor. It integrates the concept of hierarchical texton mining and data driven kernel learning into a uniform framework. The proposed method is applied to a practical medical diagnosis problem of classifying different stages of Age-Related Macular Degeneration (AMD) using a dataset comprising long-wavelength Optical Coherence Tomography (OCT) images of the choroid. The results demonstrate the feasibility of our method for classifying different AMD stages using the textural information of the choroidal region.