Нозологический спектр генодерматозов в 12 районах Ростовской области и популяциях европейской части России

The genetic epidemiological analysis of the diversity of hereditary skin diseases (HSD) among the population of the Rostov Region is presented. The aim of the research: to describe the diversity of HSD in 12 districts of the Rostov region and to conduct a comparative analysis of the diversity of HSD in different regions of the European part of Russia. Materials and methods: The total size of totally investigated populations of Rostov Region was about 500 thousand people (12 districts). The diversity of hereditary skin diseases has been studied. Results and conclusions: The spectrum of HSD is represented by 20 nosological forms, including 13 - AD, 5 - AR and 2 with X-linked types of inheritance. An analysis of the prevalence of individual HSD in the Rostov Region compared to the previously surveyed populations of the European part of Russia showed the accumulation of 6 nosological forms with autosomal dominant type of inheritance: type 1 neurofibromatosis, tuberous sclerosis, congenital hypotrichosis, monilethrix, bullous form of ichthyosiform erythroderma, bullous epidermolysis, Kobner type.