Fabrication of succinic acid-γ-Fe2O3 nano core –shells

Abstract Core–shell nano-structures were synthesized by adsorbing succinic acid on γ-Fe 2 O 3 nanoparticles (hereafter referred to as core–shell nanoparticles or core–shells). Streptomycin was chosen as a model drug to attach on γ-Fe 2 O 3 core–shells. Vibration spectroscopic data confirmed the specific adsorption of organic ligands (i.e., succinic acid or streptomycin) onto γ-Fe 2 O 3 via bi-dentate, bi-nuclear complex. Possible molecular configurations between organic ligands and γ-Fe 2 O 3 were examined by density functional theory (DFT) using Fe 6 (OH) 18 (H 2 O) 6 ring cluster. The measured vibration frequencies and bond distances (i.e., Fe O Fe, Fe O w , and Fe OH units) of the optimized γ-Fe 2 O 3 cluster matched well with the calculations.