Incidence of upper digestive tract inflammation in children with acute lymphoblastic leukemia at diagnosis.

: Inflammatory lesions in upper digestive tract are common adversary events in children with acute lymphoblastic leukemia (ALL). However, when these lesions initiate is still not clear. In this study, we retrospectively analyzed the endoscopic detection results of 129 children who suffered from ALL at diagnosis. 107 (82%) patients were found with gastrointestinal inflammation, of which 101 patients had lesions in the stomach, 11 had lesions in the esophagus and 51 had lesions in the duodenal bulb. Only 2 patients were found with helicobacter pylori infection, and 1 patient was found with a mycotic infection in the esophagus. We demonstrate that most patients with ALL have gastrointestinal inflammation at the diagnosis of the basic disease, and in contrast to adult patients in China, these inflammatory lesions were mostly not caused by HP infection.