Association study of vascular endothelial growth factor and polymorphisms of its gene with ectopic pregnancy.

The incidence of ectopic pregnancy (EP) has increased and accounts for 2% of all pregnancies. Ectopic pregnancy is a major cause of maternal morbidity and mortality, accounting for 9–13% of the first trimester pregnancy-related deaths. It is an important cause of maternal deaths in early pregnancy because most fatal cases result from delayed diagnosis and inappropriate investigation. In spite of high-resolution vaginal ultrasound and high sensitive quantitative beta-hCG assays, at first