On the molecular weight of bilirubin oxidase from Penicillium janthinellum

Abstract When bilirubin oxidase from Penicillium janthinellum was treated with bilirubin BOX was dissociated to the compound with the molecular weight between 0.5 kDa and 5 kDa. When BOX was treated with EDTA, a remarkable increase of the reaction rate was observed. The reaction mechanism of these effects is discussed.