Acid derivative (2-heteroarylamino) succinic

A compound represented by formula (1) generally following: ** ** Formula or a pharmacologically acceptable salt thereof, wherein R1 represents an aromatic hydrocarbon ring which may have 1 or 2 substituents independently selected from the group substituent group α, or an aromatic heterocyclic group which may have 1 or 2 substituents independently selected from the substituent group α; the substituent α group represents the group consisting of a halogen atom, an alkyl group C1-C4, alkyl halo C1-C4, a C1-C4 group, a C3-C6, and ring aromatic hydrocarbon group which it can be substituted with R4; R2 represents a hydrogen atom, a C1-C4 alkyl or a heterocycloalkyl group of 4 to 7 members; R3 represents a hydrogen atom or a C1-C4 alkyl; R4 represents a cyano group, a halogen atom, or a C1-C4 alkyl; A represents a hydrogen atom or a hydroxy group; L represents a group represented by the formula -NHCO- or a group represented by the formula -OCH2-; and X represents a nitrogen atom or a group represented by the formula> = CH-.