Study on the main pharmacodynamics research of Red Ochre and Magnetite Sedative capsule

Objective After the mice take Red Ochre and Magnetite Sedative capsule,through observe independent activities,sleeping time,anticonvulsive and hippocampus neurotransmitter content determination of rats experimental indexes,for determining its pharmacodynamics research. Methods Observe the drug on independent living influence of the mouse. Use mebumalnatrium caused by sleeping to observe the influence of sleep time. Use sub-threshold dose of mebumalnatrium to observe the influence of sleep rate,use nikethamide injection and electric stimulation in mouse induced convulsion to observe the anticonvulsant action. Use ELISA kit measurement test in rats single amine neurotransmitter content influence. Results Red Ochre and Magnetite Sedative capsule in mice can reduce the number of independent activities,extend the mebumalnatrium of sleep time,improve mice subthreshold dose of sleeping time,and play the anticonvulsant effects. It also can reduce rats in norepinephrine and dopamine,five hydroxide indole acetic acid content. Conclusion Red Ochre and Magnetite Sedative capsule has sedative,hypnotic,anticonvulsive effects and can reduce the hippocampus monoamine transmitters in action.