Mixed malignant germ cell tumor of ovary
2011
Introduction. Malignant tumours of ovary germ epithelium are very rare and
account for about 2-5% of all ovarian tumours of germ origin. In adolescent
patients under 20 years of age diagnosed to have ovarian tumour, these
tumours originate from germ cells in about 70% of cases. Depending on the
stage of the disease, medical treatment and age, the death rate ranges from
25% to 84%. A special group of germ tumours are mixed germ cells tumours
built of two or more different types of germ tumours. Case report. This paper
gives a diagnostic-therapeutic procedure and the clinical picture with the
course and outcome of the decease in a nineteen-year old patient with a mixed
malignant germ tumour (dysgerminoma, choriocarcinoma, immature teratoma)
found in one of the ovaries. It also deals with the appearance and
development, some characteristics and histological build of the tumours
diagnosed in this case. Conclusion. Malignant tumours of ovary germ
epithelium are very rare and develop in female population under 30 years of
age. They are characterized by a high degree of malignity. They are resistant
to cytostatic treatment, they spread very quickly with the lethal outcome.
The course of the disease is not characteristic and is usually masked under
some other acute gynaecological disease. The definitive diagnosis is made
after laparotomy and pathohistological analysis of the tumour tissue.
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