Современные экспериментальные модели депрессии
2013
This review covers basic fundamental models of experimental modeling of depression and methods of experimental modeling of behavioral alterations. Animal models are promising enough for the understanding of psychopathotology, but not as a deviations of behavior, as well as a series of psychological processes that obey certain laws. Creating models of depression is experiencing a period of prosperity. There are several models of depression: chronic mild stress model, social conflict model, leaned helplessness model, waterimmersion model. Many of them are based on some manipulation of the animals behavior, which have know biological effects. The investigation of the behavior of laboratory animals and modeling of depression allows detail characteristic features of psychopatology in humans.
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