Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors.

C.D. Andersson,Nina Forsgren,Christine Akfur,Anders Allgardsson,Lotta Berg,Cecilia Engdahl,Weixing Qian,Fredrik Ekström,Anna Linusson

Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors.

2013

C.D. Andersson
Nina Forsgren
Christine Akfur
Anders Allgardsson
Lotta Berg
Cecilia Engdahl
Weixing Qian
Fredrik Ekström
Anna Linusson

The molecular interactions between the enzyme acetylcholinesterase (AChE) and two compound classes consisting of N-[2-(diethylamino)ethyl]benzenesulfonamides and N-[2-(diethylamino)ethyl]benzenemet ...

Keywords:

Enzyme
Biochemistry
Organic chemistry
Hydrolase
Binding site
Stereochemistry
Biphenyl compound
Structure–activity relationship
Cholinesterase
Acetylcholinesterase
Chemistry
Enzyme assay

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