A randomized clinical trial of neurally adjusted ventilatory assist versus conventional weaning mode in patients with COPD and prolonged mechanical ventilation.

performed every 24 hours. The results correlated with the clinical parameters. Results: There were significantly higher asynchrony incidence rates in the whole group after using Edi catheter (before vs post-Edi catheter insertion =60.6% vs 87.9%, P,0.001). Asynchrony index: before vs post-Edi catheter insertion =7.4%±8.5% vs 13.2%±13.5%, P,0.01. Asynchrony incidence: NAVA vs conventional =0% vs 84.2%, P,0.001. Asynchrony index: NAVA vs conventional =0 vs 11.9±11.2 (breath %), P,0.001. The most common asynchrony events were ineffective trigger and delayed trigger. Conclusion: Compared to conventional mode, NAVA mode can significantly enhance respira tory monitoring and improve patient-ventilator interaction in COPD patients with prolonged mechanical ventilation in respiratory care center.