Novos Horizontes para abordagem do infarto agudo do miocárdio com supradesnivelamento do segmento ST

Nas ultimas decadas, houve reducao da mortalidade por infarto agudo do miocardio com supradesnivelamento do segmento ST (IAMCSST) associada a um conjunto de acoes que une avancos tecnologicos e politicas publicas. Entretanto, sua caracteristica de doenca tempo-dependente ainda e responsavel por elevado numero de casos de morte subita e as consequencias da reperfusao tardia ou ineficiente estao relacionadas a ocorrencia de insuficiencia cardiaca e maior morbimortalidade. Sob esse ponto de vista, foram revisados tres diferentes aspectos: o impacto das arritmias ventriculares no atendimento pre-hospitalar; a influencia do fator de Von Willebrand e o papel das microparticulas no diagnostico da doenca. (AU) In the past decades, there was a reduction in mortality from ST segment elevation acute myocardial infarction (STEMI) associated with a set of actions combining technological advances and public policies. However, its characteristic of a time-dependent disease is still responsible for a high number of cases of sudden death and the consequences of late or inefficient reperfusion are related to heart failure and increased morbidity and mortality. From this point of view, three different aspects were reviewed: the impact of ventricular arrhythmias in prehospital care; the influence of Von Willebrand factor and the role of microparticles in the diagnosis of the disease. (AU)