Delayed hypersensitivity due to epidural block with ropivacaine

Ropivacaine, introduced in 1995, is an amide-type local anaesthetic. It consists of pure optical S-(-)-isomers and has a low cardiotoxicity. We report delayed hypersensitivity reactions to ropivacaine. A 74 year old man with postherpetic neuralgia started taking amitriptyline, alprazolam, and loxoprofen and underwent an epidural block with 0.2% ropivacaine hydrochloride without preservatives (48 ml or 96 ml daily). He had no history of …