Early cryoprecipitate transfusion versus standard care in severe postpartum haemorrhage: a pilot cluster-randomised trial.

The trial was prospectively registered on ISRCTN (12146519). The trial was approved by the NHS LondonBrighton and Sussex Research Ethics Committee and the NHS Confidentiality Advisory Group. The study was funded by Barts Charity. We would like to acknowledge the support of the Joint Research Management Office, Queen Mary University of London as sponsor for the study; the contributions of members of Katie's Team, the East London women's health research patient and public advisory group; and the clinical, laboratory and maternity research teams at Barts Health NHS Trust hospitals and Homerton University Hospital. We are also grateful for all the support and advice provided by the project steering committee chaired by an independent consultant anaesthetist (M. Wilson, University of Sheffield), with four other independent members: A. Khalil, St George's University Hospital; B. Leurent, London School of Hygiene and Tropical Medicine; N. Moss, lay representative; and S. Robinson, Guy's and St Thomas' NHS Trust. No other external funding or competing interests declared.