Capsaicin inhibits lipopolysaccharide-induced adrenal steroidogenesis by raising intracellular calcium levels

Leonardo Gomes Braga Ferreira,Jessika P. Prevatto,Hércules Rezende Freitas,Ricardo Augusto de Melo Reis,Patrícia M.R. e Silva,Marco A. Martins,Robson Xavier Faria,Vinicius F. Carvalho

Capsaicin inhibits lipopolysaccharide-induced adrenal steroidogenesis by raising intracellular calcium levels

2019

Leonardo Gomes Braga Ferreira
Jessika P. Prevatto
Hércules Rezende Freitas
Ricardo Augusto de Melo Reis
Patrícia M.R. e Silva
Marco A. Martins
Robson Xavier Faria
Vinicius F. Carvalho

Introduction Glucocorticoid release by adrenals has been described as significant to survive sepsis. The activation of transient receptor potential vanilloid type 1 (TRPV1) inhibited ACTH-induced glucocorticoid release by adrenal glands in vitro.

Keywords:

TRPV1
Internal medicine
Transient receptor potential channel
Biology
Endocrinology
Lipopolysaccharide
Calcium
Sepsis
Glucocorticoid
Capsaicin
Calcium in biology
Stimulation
Corticosterone

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