Effect of total gaseous hypoxia on the frequency of occurrence and types of neoplasms in irradiated animals

: The study of neoplasm patterns and frequency in F1(CBAxC57BL) mice totally exposed to a single dose of gamma-radiation (2.5-5.5 Gy) under gaseous hypoxia conditions established a sharp drop in the incidence of mammary gland cancer as compared with a similar experiment conducted in air. Longer mean survival time following exposure in hypoxia was chiefly attributed to the beneficial effect of the latter in the course of postradiation sclerotic development in vital organs.