CSF-Venous Fistulas: Anatomy and Diagnostic Imaging.
2021
CSF-venous fistulas (CVFs), first described in 2014, represent an important cause of spontaneous intracranial hypotension (SIH). CVFs can be challenging to detect on conventional anatomic imaging because, unlike other types of spinal CSF leak, they do not typically result in pooling of fluid in the epidural space, and imaging signs of CVF may be subtle. Specialized myelographic techniques have been developed to help with CVF identification, but these techniques are not yet widely disseminated. This article reviews the current understanding of CVFs, emphasizing correlations between venous anatomy and imaging findings as well as potential mechanisms for pathogenesis, and describes current imaging techniques used for CVF diagnosis and localization. These techniques are broadly classified into fluoroscopy-based methods, including digital subtraction myelography and dynamic myelography, as well as cross-sectional methods, including decubitus CT myelography and MR myelography with intrathecal gadolinium. Knowledge of these various options, including their relative advantages and disadvantages, is critical in the care of patients with SIH. Investigation is ongoing, and continued advances are anticipated in understanding of CVFs as well as in optimal imaging detection.
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