Ischemic neuropathy with conduction blocks

We present a patient with a clinical picture of multiple mononeuropathy in which muscle and sural nerve biopsy revealed the existence of vasculitis compatible with panarteritis nodosa. Along with classical axonal lesion signs, we observed multifocal conduction blocks (CB) in all the nerves explored electrophysiologically. Topographic evolution was atypical in that distal BC disappeared earlier, whereas proximal BC appeared later and in all cases persisted longer. Ischemia may play a pathogenic role in BC along with other more well-known factors such as compression and immunological processes. BC detection would probably be less exceptional if, when ischemic neuropathy is suspected, patients were subjected to early and follow-up electrophysiological exploration that included proximal nerve segments.