Effect of Consumption of Coleus tuberosus on the Lipid Profile of Alloxan-induced Diabetic Rats

Coleus tuberosus is a minor vegetable belonging to the Lamiaceae family. C. tuberosus and processed products have been evaluated on resistant starch content and effect of consumption of C. tuberosus and processed products on the lipid profile has been studied in rats with diabetes mellitus. Resistant starch was analyzed using the megazyme method. Analysis of lipid profile was performed in experimental alloxan-induced animals. Such lipid profile as Total Cholesterol (TC), Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL) are determined enzymatically by the Cholesterol Oxidase-oxidase-Phenol Aminophenazone (CHOD-PAP) method. Triglyceride levels are determined by the enzymatic Glycerol-3-Phosphate Oxidase-Phenol+Aminophenazone (GPO-PAP) method. The results showed that the treatment process can increase the levels of resistant starch. C. tuberosus consumption and processed products can lower the lipid profile of TC, TG and LDL and increase HDL in experimental animals. Resistant starch contained in C. tuberosus and processed products is one of the factors that affect the lipid profile of experimental animals with diabetes mellitus.