Abstract 544: microRNA181c Activates Mitochondrial Calcium Uptake by Regulating Micu1 in the Heart

Hemanth N. Banavath,Barbara Roman,Brian O’Rourke,Mark J. Kohr,Elizabeth Murphy,Charles Steenbergen,Samarjit Das

Abstract 544: microRNA181c Activates Mitochondrial Calcium Uptake by Regulating Micu1 in the Heart

2019

Hemanth N. Banavath
Barbara Roman
Brian O’Rourke
Mark J. Kohr
Elizabeth Murphy
Charles Steenbergen
Samarjit Das

Translocation of miR-181c into heart-mitochondria downregulates the mitochondrial gene, mt-COX1. miR-181c/d-/- hearts experience less oxidative stress during I/R and are protected against I/R injur...

Keywords:

Cardiology
Mitochondrial calcium uptake
Internal medicine
Biology
Diabetes mellitus
Pharmacology
Calcium
Mitochondrial DNA
Chromosomal translocation
microRNA
Cell biology
Mitochondrion
Oxidative stress

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