Practical Synthesis of a Stable Precursor for Positron Emission Tomography Imaging Agent 18F-GTP1

Nicholas A. White,Kyle Clagg,Lauren E. Sirois,Ngiap-Kie Lim,William A. Nack,Paul D. O’Shea,Haiming Zhang,Francis Gosselin

Practical Synthesis of a Stable Precursor for Positron Emission Tomography Imaging Agent 18F-GTP1

2020

Nicholas A. White
Kyle Clagg
Lauren E. Sirois
Ngiap-Kie Lim
William A. Nack
Paul D. O’Shea
Haiming Zhang
Francis Gosselin

18F-GTP1 is a deuterated small molecule positron emission tomography (PET) imaging agent used to visualize tau tangles in Alzheimer’s disease patients. The first-generation synthesis of 18F-GTP1’s ...

Keywords:

Positron emission tomography
Nanotechnology
Chemistry
Inorganic chemistry
Imaging agent

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