Эволюционная изменчивость вирусов гриппа b, циркулировавших в Российской Федерации с 2005 по 2012 г

Specific traits of influenza B viruses circulation in Russia and worldwide in 2005-2012 were studied and the Amount of influenza B viruses in the whole population of influenza viruses isolated in Russia was estimated. The trend toward antigenic drift for both victoria and Yamagata lineages was characterized. The genetic analysis revealed amino acid changes that influenced the antigenic properties of the viruses. The match of the epidemic isolates and vaccine strains was corroborated.