Mesoporous Silica Anchored Ru Catalysts for Highly Enantioselective Hydrogenation of ?-Ketoesters.

Recyclable and reusable mesoporous silica anchored Ru catalysts based on 4,4′-substituted BINAPs were synthesized and used for the hydrogenation of β-alkyl β-ketoesters with up to 98.6% e.e. and β-aryl β-ketoesters with up to 95.2% e.e.