Eritrodermia en 3160 pacientes internados en clínica médica

2007 
La eritrodermia es una enfermedad inflamatoria cutanea generalizada. Generalmente se presenta en la edad media de la vida y en la mayoria de los casos es debida a exacerbacion de dermatosis preexistentes. Puede asociarse a manifestaciones sistemicas como poliadenopatias, hepatomegalia, eritrosedimentacion acelerada, leucocitosis y/o eosinofilia, entre otros. Con el fin de conocer la incidencia y la etiologia de esta patologia en nuestro hospital realizamos un estudio retrospectivo y observacional sobre 3160 historias clinicas de pacientes internados en el servicio de clinica medica. Detectamos 25 casos de eritrodermia lo cual implica una incidencia del 0.79%. La edad media de presentacion fue 48 anos. La etiologia mas frecuente fue la secundaria a medicamentos, siendo los β lactamicos los mas involucrados. La alteracion sistemica mayormente observada fue la eosinofilia (62%). El comienzo de la enfermedad en la mayoria de los casos fue agudo.(AU) Erythroderma is an inflammatory and generalized skin disorder (more than 90% of the body surface area) accompanied by a variably degree of scaling. Often affects middle ages of life and it is usually caused by the exacerbation of a preexisting dermatoses. It could be associated to systemic manifestations like lymphadenopathy, liver enlargement, leukocytosis and elevated erythrocyte sedimentation. The aim of this study was to determinate the incidence and also the etiology of this pathology in our environment. We made a retrospective and observable study based on the research of 3160 clinic stories of patients that were in the hospital at the Clinical Department. We found that 25 patients were diagnosed with erithroderma (incidence 0.79%). The mean age at diagnosis was 48 years. The most common causative factor was drug reactions been the β lactams the most involved drug. Eosinophilia was the most important systemic manifestation (62%). The onset of erithroderma was usually abrupt and florid.(AU)
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