Demonstration of lanthanum in liver cells by energy-dispersive X-ray spectroscopy, electron energy loss spectroscopy and high-resolution transmission electron microscopy
2006
Summary The appearance of lanthanum in liver cells as a result of the injection of lanthanum chloride into rats is investigated by advanced transmission electron microscopy techniques, including electron energy loss spectroscopy and high-resolution transmission electron microscopy. It is demonstrated that the lysosomes contain large amounts of lanthanum appearing in a granular form with particle dimensions between 5 and 25 nm, whereas no lanthanum could be detected in other surrounding cellular components.
Keywords:
- Electron energy loss spectroscopy
- Scanning confocal electron microscopy
- Lanthanum
- Particle
- High-resolution transmission electron microscopy
- Analytical chemistry
- Energy filtered transmission electron microscopy
- Energy-dispersive X-ray spectroscopy
- Chemistry
- Transmission electron microscopy
- Nuclear magnetic resonance
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