Isolation of Venezuelan Equine Encephalomyelitis Virus by Bone Marrow Culture.

SummaryIn vitro culture of bone marrow obtained relatively late in the course of disease in both man and monkeys has resulted in isolation of VEE virus not detected by conventional procedures. Viable marrow cells served as both the source of virus and as susceptible tissue supporting virus multiplication. It is suggested that this method may have application in the diagnosis of other viral diseases.The professional and technical assistance of W. R. Brunton, K. M. Goddard, and R. C. Carter is gratefully acknowledged.