Effects of fenvalerate on enzymes of rat liver cell membranes and microsomes

By exploring the effects of fenvalerate on enzymes of rat liver cell membranes and microsomes, it was found that fenvalerate inhibited the activities of liver plasma membrane-bound 5′-Nase and ALP in different extent, induced microsomal AH activity and increased cytochrome P-450 content. A preliminary study was made to elucidate the possible mechanism of these effects.