P3-202Best supportive care for advanced lung cancer patients aged 85 and older

Abstract Background In Japan, the rate of the elderly population is rising, and elderly lung cancer patients are also increasing. Because of their genetic and environmental factors, they often received only best supportive care (BSC). Methods We performed retrospective analysis of 25 patients with advanced lung cancer patients aged 85 and older since 2014 to 2017 and assessed Background and prognosis. Results The age was 85-94 years, and 17 patients were male. Thirteen patients had malignant pleural effusion. In these cases, 10 were adenocarcinoma (3 harboring EGFR mutation), 6 squamous cell carcinoma, 4 NSCLC-NOS, 2 SCLC, and 3 unknown. Nine patients were assigned an ECOG good PS of 0,1,2, and 16 patients a poor PS of 3,4. The common reasons of patients who received BSC with PS (13 patients) and cognitive-function disorder (6 patients). Median overall survival were 2.7 months. According to univariate analysis (Cox proportional analysis),PS=3 or 4 [hazard ratio: 5.94, 95% confidence interval (C.I): 1.77-19.93] and hypoalbuminemia (serum albumin Conclusion In elderly patients, BSC had often been selected for reasons other than aggressive disease. Since the elderly population is expected to rise further in the future, it is important to construct a palliative treatment strategy that takes into consideration the characteristics of the elderly.