Comparison of two irradiation methods for laryngeal carcinoma in the second degree of clinical progression

: Two methods of irradiation of larynx carcinoma have been compared: conventional dose fractionation and hyperfractionation. The first consisted in irradiating once a day a dose of 2.2 GY to the complete dose of 70 Gy to 77 Gy, and the other in applying two fractions daily, 1.1 Gy each, until the combined dose of 70 Gy to 77 Gy was reached. 20 patients irradiated conventionally and 32 treated with hyperfractionation have been examined. The proportion of complete remissions in the compared groups was 65% and 72% respectively. A better tolerance of irradiation by means of hyperfractionation has been recorded. The proportion of I degree and II degree reactions in that group of patients was 75% whereas it was 65% in the group irradiated conventionally.