Advancing the Treatment for Chagas' Disease

It is estimated that 8 million people are infected with Trypanosoma cruzi worldwide, with the majority of cases occurring in the Latin American countries in which the parasite is endemic. However, cases of Chagas' disease have been increasingly detected in the United States, Canada, many European countries, and some Western Pacific countries, owing primarily to an increase in population movements between Latin America and other continents. Moreover, some countries in which the parasite is not endemic have higher estimated numbers of cases than many endemic countries in Latin America (e.g., >300,000 cases in the United States and >50,000 in Spain). . . .