Distribution and Drug Resistance of Pathogens in Blood Culture Specimens: A Survey of 7506 Cases in a General Hospital

OBJECTIVE To explore the distribution and drug resistance of pathogens in blood culture specimens between 2003 and 2008 in our hospital.METHODS The blood culture results in the past six years were analyzed retrospectively by WHONET 5.3 software.RESULTS In the past six years,the pathogenic bacteria including 441 strains of Gram-negative bacteria,300 strains of Gram-positive bacteria,53 strains of fungi,3 strains of anaerobic bacteria and 7 strains compounded bacteria were isolated and accounted for 54.85%,37.31%,6.59%,0.37% and 0.87%,respectively.Some antibiotics showed higher susceptibility,for instance,imipenem and cefoperazone/sulbactam against Gram-negative bacteria and vancomycin,teicoplanin and linezolid against Gram-positive bacteria.CONCLUSIONS It is important for patients with suspected septicemia to strengthen pathogens detection.