Localization of entodermal antigen in organs and tissues of dogs

: Spontaneous stomatitis in dogs gives rise to the appearance in ectodermal derivatives of an additional antigen that is not detectable in normal oral mucosa. The immunofluorescence and immunoperoxidase methods were used to study the intracellular localization of entodermal antigen in various part of the alimentary tract. Clear and contrast localization of the test antigen in all parts of the alimentary tract warrants a conclusion that this antigen is a mucus component secreted by alimentary tract glands. No antigen under test was found in oral mucosa portions of entodermal origin except for soft palate. Entodermal antigen was not detected either in small mucus-forming glands.