Modeling Approach for Oxygen Exchange in the Human Lung under Hypobaric Conditions

Abstract : Physical effort at high altitude can result in serious complications in the human respiratory system even for healthy and well-trained persons. For people with a pulmonary disorder already a stay at moderate altitude or transportation by air (e.g. in ease of moderate medical evacuation) can lead to significant problems caused by hypoxemia. In both circumstances the oxygen tension of the inspired air (PI,O2) and therefore of the arterial blood (Pa,O2) drops substantially.