Analysis of the Etiologies and Clinical Characteristics of 129 Cases of Neonatal Cyanosis

Objective:To explore the etiologies and clinical characteristics of neonatal cyanosis.Methods:The clinical data of 129 cases of cyanotic neonates from Jan 2007 to Dec 2008 in hospital were analyzed retrospectively.Results:(1)Of 129 cases of cyanotic neonates,primary pulmonary diseases were the most common cause of cyanosis.There were 101 cases(78.3%) of central cyanosis,among which 92 cases(71.3%) were pulmonary cyanosis and only 9 cases(7.0%) were cardiac cyanosis;13 cases(10.1%) were peripheral cyanosis;15 cases(11.6%) were other cyanosis.(2)TcSO2 monitoring and relevant examination were performed in 129 cases of cyanotic neonates at once after admission.Different patterns of oxygen therapy were given according to patient's condition.Before oxygen therapy,TcSO2 in 101 cases of central cyanotic neonates was all below 85%.Of these 101 cases,after oxygen therapy 76 cases of pulmonary cyanosis disappeared and TcSO2 was above 85% while the other 25 cases of cyanosis didn't disappear and TcSO2 was still below 85%;Among 25 cases of central cyanotic neonates whose oxygen therapy didn't yield good results,13 cases were ill with pulmonary diseases accompanied with persistent fetal circulation,9 cases were ill with compound congenital heart diseases and 3 cases with congenital developmental anomaly of diaphragma.Before oxygen therapy,TcSO2 in 13 cases of peripheral cyanotic neonates was all above 85%.Of these 13 cases,8 cases of cyanosis were slightly alleviated after oxygen therapy and 5 cases diagnosed bruising were called off oxygen therapy.Of 15 cases of other cyanotic neonates,cyanosis didn't acquire improvement after oxygen therapy.Conclusion:Primary pulmonary diseases are the most common cause of neonatal cyanosis.Oxygen therapy is basic treatment method of cyanosis,but its results may have obvious difference because of different cyanotic cause