Alkaloids from the leaves and stem bark of Ervatamia malaccensis

Abstract Chemical investigation of the leaves and stem bark of Ervatamia malaccensis afforded two novel alkaloids, N (1)-methoxymethuenine and N (1)-methoxy-19,20-dehydroervatamine together with the known alkaloids: 19,20-dehydroervatamine, 20-epiervatamine, methuenine, 16-epimethuenine, 6-oxomethuenine and dregamine. Structural elucidation of the new alkaloids was based on spectral data and on a chemical correlation.