EFFECTS OF A NOVEL INTERACTING MOLECULE WITH AT1 RECEPTOR, ATRAP, ON ANG II-INDUCED PROLIFERATIVE ACTIVITY AND OXIDATIVE STRESS IN VASCULAR SMOOTH MUSCLE CELLS

Objective:Superoxide anions are recognized as mediators of intracellular signaling cascades and are known to participate in cardiovascular diseases such as arteriosclerosis and hypertension. Previous studies reported that the production of superoxide is modulated by many factors including Ang II - A