Identification of a Potent and Rapidly Reversible Inhibitor of the 20S‐Proteasome.

Ashok V. Purandare,Honghe Wan,Naomi Mae Laing,Khalid D. Benbatoul,Wayne Vaccaro,Michael A. Poss

Identification of a Potent and Rapidly Reversible Inhibitor of the 20S‐Proteasome.

2004

Ashok V. Purandare
Honghe Wan
Naomi Mae Laing
Khalid D. Benbatoul
Wayne Vaccaro
Michael A. Poss

Synthesis and in vitro characterization of novel, lactam boronic acid based, selective, and rapidly reversible inhibitor 14 of the 20S-proteasome is presented.

Keywords:

Biochemistry
Proteasome
Organic chemistry
Chemistry
20s proteasome

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