Atorvastatin calcium oral disintegrating tablet and preparation method thereof

2010 
The invention provides an atorvastatin calcium oral disintegrating tablet prescription and a preparation method thereof. The atorvastatin calcium oral disintegrating tablet prescription comprises atorvastatin calcium, a bitter covering agent, a filling agent, a disintegrant, a lubricant, and the like. The invention is technically characterized by providing a particle preparing technology which not only can effectively cover the bitter of the atorvastatin calcium, but also can lead the atorvastatin calcium oral disintegrating tablet to be disintegrated in the mouth. The atorvastatin calcium oral disintegrating tablet with pressure of above 4Kg and disintegrating time within 30 seconds can be prepared by adding normal supplementary materials of filling agents, disintegrants, lubricants, and the like of oral disintegrating tablets and is easy to realize industrial scale production.
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