New biosurfactants containing β-lactam and triazole rings

We report the synthesis and the properties of a new class of monobactams containing a triazole ring, that are both bio- and surface-active materials. A standard procedure for β-lactam synthesis from fatty amines, aminoacid, and 2,2-bis (hydroxymethylpropionic acid), involves an intramolecular reaction. After introduction of an azido group, the reaction with acetylenic derivatives leads to a triazole ring. The critical micelle concentrations of aqueous solutions have been determined; antibiotic and antiviral activities have been evaluated.