Effect of Oleozon on Healing of Exposed Pulp Tissues

Objective: To compare the healing effect of Oleozon and calcium hydroxide on experimentally exposed pulp tissue. Method: Direct pulp exposures were conducted in nine dogs, i.e., three dogs were prepared for each experimental period of 7, 30 and 90 days. In each dog the upper and lower canines of the right side were capped with calcium hydroxide (Dycal), while those of the left side were capped with ozonated olive oil (Oleozon). After the observation periods, the teeth were prepared for histomorphological examination. Results: The tissues capped with Oleozon revealed inflammation with dilated blood vessels and hemorrhages at 7 days, a slight inflammatory response at 30 days, and the increase of collagen fibers and fibroblast with dilated blood vessels at 90 days. While, the tissues capped with calcium hydroxide exhibited medium degree of inflammation and necrosis adjacent to the exposure site at 7 days, remarkable absorption of necrotic tissues with few collagen fibers and fibroblast at 30 days, and a localized connective tissue capsule with depositions of reparative dentin at 90 days. Conclusion: Based upon the results and the limitations of the study, it was concluded that direct pulp capping with Oleozon induced less degrees of irritation to the dental pulp compared to that with Dycal. Clinical significant: The application of Oleozon paste for direct capping to exposed pulp could have a possibility to serve as a therapeutic method to enhance pulp tissue healing. (Rania Sayed Mosallam; Amany Nemat; Ahmed El-Hoshy and Shiro Suzuki. Effect of Oleozon on Healing of Exposed Pulp Tissues. Journal of American Science 2011;7(5):38-44). (ISSN: 1545-1003). http://www.americanscience.org .