Micrornas as diagnostic and prognostic biomarkers

The intensive development of molecular biology and biochemistry in recent years has allowed the disclosure of intimate mechanisms of a number of processes in the cell. Numerous molecules have become useful tools for diagnosing and predicting a number of diseases. These are, for example, the small, non-coding micro RNAs (miRNAs). It was found that the majority of protein-coding genes contain miRNA-binding sites under selective pressure (1) that make them the master regulators of cellular processes. Thus