Safety of carotid endarterectomy for the patiets with carotid artery stenosis and coronary artery disease under dual antiplatelet therapy

Objective To study the safety of dual antiplatelet therapy prior to carotid endarterectomy in the patients with carotid artery stenosis and Coronary Artery Accident. Methods We review 86 patients with carotid artery stenosis and Coronary Artery Accidents who admitted in Peking University International Hospital between 2017 January and 2019 March. The 86 patients undergo carotid endarterectomy with dual antiplatelet therapy. We evaluate the safety of carotid endarterectomy dunring the dual antiplatelet thrapy by analyzing the incidence of acute coronary syndrome, ischemic cerebrovascular accident, intracranial hemorrhage, and regional hematoma. Results From 2017 January to 2019 March, 86 patients with carotid artery stenosis and Coronary Artery Accident continued dual antiplatelet therapy prior to carotid endarterectomy. The incidence of main perioperative complications were as follows: acute coronary syndrome: 0; asymptomatic ischemia cerebrovascular accident: 8.1% (7/86); symptomatic ischemia cerebrovascular accident: 0; intracranial hemorrhage:0; neck hematoma:13.9%(13/86). All the patients were followed 30 days after the procedure. The modify Rakin Scale of the patients were all <3. The local hematoma were all recovered automatically without treatment and the perioperative mortality and morbidity was 0. Conclusion For the patients with carotid artery stenosis and Coronary Artery Accidents, carotid endarterectomy under dual antiplatelet therapy was a safe choice. Key words: Carotid artery stenosis; Coronary artery stenosis; Carotid endarterectomy; Dual antiplatelet therapy