Synthetic derivatives and analogues of γ-L-glutamyl-taurine, a bioactive compound from bovine parathyroids

γ-L-Glutamyl derivatives and a β-L-aspartyl derivative of different amines (taurine, nortaurine, N-methyltaurine, taurine amide, tauryl-methylamine, tauryl-piperidine, β-alanine amide, orthanilic acid, 2-aminoethanephosphonic acid, ethanolamine-O-sulfate and ethanolamine-O-phosphate) have been synthesized by mixed anhydride or active ester coupling method. One of the dipeptide analogues, γ-L-glutamyl-(ethanolamine-O-sulfate) was prepared by esterification, too. Syntheses of α,γ-L-glutamyl-bis-taurine and of DL-2-amino-8-sulfo-octanoic acid are also described.