Study on the Optimum Harvest Time of FRUCTUS EVODIAE

[Objective] To determine the optimum harvest time of FRUCTUS EVODIAE.[Methods] The optimum harvest time of FRUCTUS EVODIAE was determined according to the apparent characteristics and the content of evodine,evodiamine and rutaecarpine in FRUCTUS EVODIAE by high-performance liquid chromatography(HPLC).[Results] In the investigated harvest time,the content change of evodine was insignificant,and the content of evodiamine and rutaecarpine first increased then slowly declined with the harvest time.[Conclusions] The proposed method was simple,rapid,accurate and reliable,and can be used as a tool for quality control of FRUCTUS EVODIAE.The optimum harvest time was during mid-to-late August.