Serotonin and psychiatric disorders : a key to new therapeutic approaches

Evidence is reviewed that 5-HT (5-hydroxytryptamine. serotonin) acting through the 5-HT 3 receptor subtype can influence behaviour relevant to anxiety, schizophrenia and cognitive disorders, and that 5-HT 3 receptor antagonists such as ondansetron (CAS 116002-70-1) can correct behavioural disturbace in the absence of effect on normal behaviour