Antibiotic adjuvants as a novel strategy to tackle antibiotic resistance

Today antimicrobial resistance is considered as one of the most important threat to global health. So it is very crucial to identify measures to overcome the different mechanisms of antibiotic resistance. Among the major approaches to tackle Antibiotic resistance, antibiotic adjuvant strategies play an important role. The antibiotic adjuvant combinations that attained clinical success include β lactamase inhibitors, efflux pump inhibitors, outer membrane permiabilisers, virulence inhibitors and nanoparticles. Preclinical and clinical trials on these different approaches are going on.