Androstane and pregnane 2β,19-hemiketal steroids from Trichilia claussenii

Abstract The methanol extract of stems of Trichilia claussenii yielded three new steroids: 2α,3α-dihydroxyandrostan-16-one 2β,19-hemiketal, 2α,3β-dihydroxypregnan-16-one 2β,19-hemiketal, 2β,3β-dihydroxypregnan-16-one. Two known steroids 2β,3β,4β-trihydroxypregnan-16-one, 2α,3α,4β-trihydroxypregnan-16-one and a mixture of sitosterol and stigmasterol β- O - d -glucopyranosides were also isolated. The structures of the isolated compounds were determined on the basis of spectroscopic analysis. © Elsevier Science Ltd. All rights reserved