Роль генетических факторов в развитии хронического пылевого бронхита у работников угледобывающих предприятий Кузбасса

The distribution of genotypes of HP, GC, EsD, AsP and polymorphisms GSTT1 (GST-θ1) and GSTM1 (GST-μ1) and NOS3 (polymorphism VNTR4) in miners with chronic dust bronchitis, and in those without this occupational disease has been studied. The carriers of genotypes of genotypes EsD 1-2, AsP bb were shown to be more prone to develop chronic dust bronchitis. Endogenous factors of resistance to the disease are the genotypes GC 1-1, EsD 1-1, AsP bc.